Episode 1: Episode 1
Release Date
Oct 09, 2025
Genre
Drama
Rating
TV-14 (L)
Network
ABC
Language
English
Episode Summary
In the Season 22 premiere, the doctors return to Grey Sloan Memorial with big hopes and fresh challenges. Friends support each other through tough patients, new romances bloom, and a surprise emergency tests the whole team. It’s a warm, exciting episode about teamwork, kindness, and never giving up.
Advertisement
Cast & Crew
Grey's Anatomy S22E1:
Shonda Rhimes
Writer
Ellen Pompeo
Actor
Chandra Wilson
Director
James Pickens Jr.
Actor
Kevin McKidd
Director
Caterina Scorsone
Actor
Camilla Luddington
Actor
Jason George
Actor
Kim Raver
Actor
Chris Carmack
Actor
Anthony Hill
Actor
Alexis Floyd
Actor
Harry Shum Jr.
Actor
Adelaide Kane
Host
Niko Terho
Actor
Mark Gordon
Executive Producer
Betsy Beers
Executive Producer
Krista Vernoff
Executive Producer
Zoanne Clack
Executive Producer
Debbie Allen
Director
Andy Reaser
Executive Producer
Meg Marinis
Writer
Linda Klein
Producer
Felicia Pride
Producer
Tameson Duffy
Writer
Sara E. White
Producer
James E. Williams
Producer
Vanessa Delgado
Producer
Rob Corn
Director
Allison Liddi-Brown
Director
Jeannot Szwarc
Director
Julie Wong
Writer
Jess Righthand
Writer
Jase Miles-Perez
Writer